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| ADHD News | |
| ADHD Drugs Do Not Raise Stroke, Heart Attack Or Sudden Cardiac Death Risk Young and middle-aged adults who are prescribed ADHD (attention deficit/hyperactivity disorder) drugs do not have a higher chance of developing serious cardiovascular events, such as sudden cardiac death, heart attack or stroke, researchers from Kaiser Permanente Northern California, Oakland, reported in JAMA (Journal of the American Medical Association). | 13 Dec 2011 |
| Alcohol / Addiction / Illegal Drugs News | |
| Risk Of Death And Stroke In Those With Heart Disease Increased By Herbal Amphetamine Chewing the natural stimulant khat increases the risk of death and stroke in patients with heart disease compared to those who are not users, according to new research in Circulation: Journal of the American Heart Association. | 13 Dec 2011 |
| Allergy News | |
| Few Allergies In Unstressed Babies A new study from the Swedish medical university Karolinska Institutet shows that infants with low concentrations of the stress-related hormone cortisol in their saliva develop fewer allergies than other infants. | 13 Dec 2011 |
| Anxiety / Stress News | |
| Few Allergies In Unstressed Babies A new study from the Swedish medical university Karolinska Institutet shows that infants with low concentrations of the stress-related hormone cortisol in their saliva develop fewer allergies than other infants. | 13 Dec 2011 |
| Preventing A Traumatism From Establishing Itself And Becoming Pathological The study, initiated by the Swiss researchers and published in Nature, constitutes ground-breaking work in exploring emotions in the brain.Anxiety disorders constitute a complex family of pathologies affecting about 10% of adults. | 13 Dec 2011 |
| Back Pain News | |
| Lower Back Pain - MRI Does Not Improve Outcomes For Epidural Steroid Injection Candidates According to an investigation published Online First by the Archives of Internal Medicine, one of the JAMA/Archives journals, magnetic resonance imaging (MRI) prior to administration of epidural steroid injections (ESI), does not seem to improve outcomes for individuals with chronic lower back pain or for those with conditions like sciatica, and only has a small effect on the physician's decision making. | 13 Dec 2011 |
| Costly Diagnostic MRI Tests Unnecessary For Many Back Pain Patients Johns Hopkins-led research suggests that routine MRI imaging does nothing to improve the treatment of patients who need injections of steroids into their spinal columns to relieve pain. Moreover, MRI plays only a small role in a doctor's decision to give these epidural steroid injections (ESIs), the most common procedure performed at pain clinics in the United States. | 13 Dec 2011 |
| Bio-terrorism / Terrorism News | |
| When Planning For Terrorist Chemical Weapons, Pharmacists May Be Crucial Terrorist attacks with chemical weapons are a real possibility, according to a study that appears in the online open access Journal of Pharmacy Practice, published by SAGE. Thanks to their extensive knowledge of toxic agents, and how to treat those who have been exposed, pharmacists are an invaluable resource in the event of an actual or potential chemical weapons attack. | 13 Dec 2011 |
| Biology / Biochemistry News | |
| RUB Researchers Decipher The Role Of Proteins In The Cell Environment How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Bochum's researchers have now investigated what influence the cell environment, known as the extracellular matrix, has on this process. | 13 Dec 2011 |
| If You Care, Yawn Back! Everybody knows that yawning is contagious. When a person yawns, other people can respond by yawning. What wasn't known is that "yawn transmission" is more frequent, and faster, between people sharing an empathic bond: close friends, kin, and mates. | 13 Dec 2011 |
| Method To Produce Proteins In Laboratory Has Now Been Discovered The most abundant and important molecules in all living organisms are proteins; after all they manage to participate in every single one of life's essential reactions. So it is easy to see why scientists have been making such a fuss trying to learn how to synthesise them in laboratory as this would provide them with a tool of extraordinary potential. | 13 Dec 2011 |
| Blood / Hematology News | |
| Outpatients Experience The Most Cancer-Related Blood Clots In a study of nearly 18,000 cancer patients, University of Rochester Medical Center researchers found that when blood clots develop - a well-known and serious complication of cancer treatment - 78 percent of the time they occur when a person is out of the hospital, at home or elsewhere, while on chemotherapy. | 13 Dec 2011 |
| Study Points To Novel Way To Improve Outcomes From Umbilical Cord Blood Transplants A new method to boost the number of immune cells in umbilical cord blood prior to cord blood transplants for cancer patients appears to lead to a quicker rebuilding of a new immune system in the patient's body than with a conventional cord blood transplant procedure, according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting. | 13 Dec 2011 |
| Adults With Hemophilia B Benefit From Gene Therapy Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U. | 13 Dec 2011 |
| Bones / Orthopedics News | |
| Simple, Model-Free Analysis Of Voltage-Gated Channels A new study in the Journal of General Physiology* provides fresh insight into voltage-gated channels - transmembrane ion channels that play a critical role in the function of neuronal and muscle tissue. | 13 Dec 2011 |
| Breast Cancer News | |
| How Do BRCA1 Mutations Harm Breast Cells? Researchers Demonstrate Researchers at the Johns Hopkins Kimmel Cancer Center have demonstrated during their work with breast cells that breast cells become vulnerable to cancer if a single copy of the breast cancer gene BRCA1 is inactivated. | 13 Dec 2011 |
| In Pre-Leukemic Cells, 'PARP' Drug Sabotages DNA Repair Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits of their own DNA, causing these cells to self-destruct. | 13 Dec 2011 |
| Vaccine Developed That Attacks Breast Cancer In Mice; Implications For Ovarian, Colorectal And Pancreatic Cancers Researchers from the University of Georgia and the Mayo Clinic in Arizona have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases - including those that are resistant to common treatments. | 13 Dec 2011 |
| Cognitive Problems Still Evident Several Years After Breast Cancer Treatment A new analysis has found that breast cancer survivors may experience problems with certain mental abilities several years after treatment, regardless of whether they were treated with chemotherapy plus radiation or radiation only. | 13 Dec 2011 |
| Gene Inheritance Patterns Influence Age Of Diagnosis In BRCA Families Women who inherit the cancer genes BRCA1 or BRCA2 from their paternal lineage may get a diagnosis a decade earlier than those women who carry the cancer genes from their mother and her ancestors, according to a new study by researchers at the North Shore-LIJ Health System's Monter Cancer Center in Lake Success, NY. | 13 Dec 2011 |
| Increasing Number Of Imaging Visits Faced By Breast Cancer Patients Before Surgery Breast cancer patients frequently undergo imaging like mammograms or ultrasounds between their first breast cancer-related doctor visit and surgery to remove the tumor. Evaluations of these scans help physicians understand a person's disease and determine the best course of action. | 13 Dec 2011 |
| Cancer / Oncology News | |
| How Lymphoma Evolves - A Study Of Two Sisters A 41-year-old woman with chronic-phase chronic myeloid leukemia received a bone marrow transplant and subsequent leukocyte infusion from her sister to control her leukemia, however seven years on, both sisters developed follicular lymphoma. | 13 Dec 2011 |
| How Do BRCA1 Mutations Harm Breast Cells? Researchers Demonstrate Researchers at the Johns Hopkins Kimmel Cancer Center have demonstrated during their work with breast cells that breast cells become vulnerable to cancer if a single copy of the breast cancer gene BRCA1 is inactivated. | 13 Dec 2011 |
| Cancer Vaccine Significantly Reduces Tumor Size An experimental cancer vaccine has been found to reduce tumor size by an average of 80%, researchers from the Mayo Clinic and the University of Georgia reported in Proceedings of the National Academy of Sciences. | 13 Dec 2011 |
| Understanding How Brain Tumors Invade Scientists have pinpointed a protein that allows brain tumors to invade healthy brain tissue, according to work published this week in the Journal of Experimental Medicine*.40% of a common but deadly type of brain tumor - called glioblastoma multiforme (GBM) - have mutations in a gene that encodes a protein called epidermal growth factor receptor (EGFR). | 13 Dec 2011 |
| Outpatients Experience The Most Cancer-Related Blood Clots In a study of nearly 18,000 cancer patients, University of Rochester Medical Center researchers found that when blood clots develop - a well-known and serious complication of cancer treatment - 78 percent of the time they occur when a person is out of the hospital, at home or elsewhere, while on chemotherapy. | 13 Dec 2011 |
| Brain Tumor Chemotherapy Resistance Prediction Glioblastoma multiforme (GBM) is the most common and lethal of all human brain tumors that originate in the brain. For most patients, treatment involves surgery followed by both radiation therapy and chemotherapy with temozolomide. | 13 Dec 2011 |
| Childhood Cancer Survivors' Exposure To Chemotherapy, Radiation Does Not Increase Risk Of Birth Defects In Their Children A large, retrospective study shows that children of childhood cancer survivors who received prior treatment involving radiation to testes or ovaries and/or chemotherapy with alkylating agents do not have an increased risk for birth defects compared to children of survivors who did not have such cancer treatment. | 13 Dec 2011 |
| Dana-Farber Offers Healthy Holiday Recipes And Food Tips To Fight Cancer With Your Fork This Holiday Season The holidays are in full swing and festive food is everywhere. Some are naughty, some are nice, and some may even help fight cancer."While these so-called holiday foods are delicious to eat, they can also have the added bonus of containing cancer-preventing nutrients," says Stephanie Meyers, MS, RD/LDN, a nutritionist at Dana-Farber Cancer Institute in Boston. | 13 Dec 2011 |
| Cancer Screening In Older Patients Very Common U.S. Preventive Services Task Force guidelines recommend against routine cancer screening, especially for breast, cervical, colorectal and prostate cancer, but adults 75 and older are still receiving regular cancer screenings. | 13 Dec 2011 |
| Study Points To Novel Way To Improve Outcomes From Umbilical Cord Blood Transplants A new method to boost the number of immune cells in umbilical cord blood prior to cord blood transplants for cancer patients appears to lead to a quicker rebuilding of a new immune system in the patient's body than with a conventional cord blood transplant procedure, according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting. | 13 Dec 2011 |
| Little-Studied Cellular Mechanism Elevated To Potential Drug Target For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes from cell metabolism to programmed cell death. | 13 Dec 2011 |
| Cardiovascular / Cardiology News | |
| ADHD Drugs Do Not Raise Stroke, Heart Attack Or Sudden Cardiac Death Risk Young and middle-aged adults who are prescribed ADHD (attention deficit/hyperactivity disorder) drugs do not have a higher chance of developing serious cardiovascular events, such as sudden cardiac death, heart attack or stroke, researchers from Kaiser Permanente Northern California, Oakland, reported in JAMA (Journal of the American Medical Association). | 13 Dec 2011 |
| Dermatology News | |
| News From The Journal Of Clinical Investigation : Dec. 12, 2011 IMMUNOLOGY: Finding a new immune function for NEMO Ectodermal dysplasias are a group of inherited conditions in which there is abnormal development and function of the skin, hair, nails, teeth, and/or sweat glands. | 13 Dec 2011 |
| Researchers Say Scar Findings Could Lead To New Therapies Researchers at the Stanford University School of Medicine report that they have identified the molecular pathway through which physical force contributes to scarring in mice."Our study exposes one of the fundamental mechanisms by which the mechanical environment can directly increase inflammation, which is strongly implicated in scarring," said Geoffrey Gurtner, MD, professor and associate chair of surgery. | 13 Dec 2011 |
| Diabetes News | |
| Linagliptin Combined With Metroformin Demonstrates Meaningful Glycemic Control Improvement Boehringer Ingelheim and Eli Lilly and Company announced their results of a 24-week open label arm of a phase III study for linagliptin in initial combination with metformin at the International Diabetes Federation (IDF) World Diabetes Congress in Dubai. | 13 Dec 2011 |
| Clues To Development Of The Pancreas Provided By Rare Genetic Disorder Could Lead To Diabetes Therapy A rare genetic disorder has given researchers at the University of Exeter a surprising insight into how the pancreas develops. The finding provides a clue to how it may be possible to 'programme' stem cells - master cells in the body that can develop into specialised cells - to become pancreatic cells. | 13 Dec 2011 |
| Epilepsy News | |
| Electrical Activity In The Brain Likened To An Orchestra Researchers at the Norwegian University of Life Sciences (UMB) have developed a new method for detailed analyses of electrical activity in the brain. The method, recently published in Neuron, can help doctors and researcher to better interpret brain cell signals. | 13 Dec 2011 |
| Eye Health / Blindness News | |
| AMD Prevalence In India, China and Malaysia Similar According to an investigation being published Online First by the Archives of Ophthalmology, one of the JAMA/Archives journals, in Asia, the prevalence of age-related macular degeneration (AMD) - an eye disease connected with aging that gradually destroys sharp, central vision - is similar among individuals from India, China and Malay. | 13 Dec 2011 |
| Preventing Trichiasis Recurrence After Surgery - Study Looks At Antibiotic Therapy A study being published Online First by the Archives of Ophthalmology, one of the JAMA/Archives journals reveals that, 10% of patients who received a single dose of oral azithromycin (antibiotic) after surgery for trichiasis (a significant worldwide eye problem) experience trichiasis again compared to 13% of patients who received topical tetracycline therapy, with the protective effects apparent for up to 3 years after surgery, although not considerably different between the two medications. | 13 Dec 2011 |
| GastroIntestinal / Gastroenterology News | |
| Private Rooms In Hospitals Does Not Reduce The Incidence Of Gastroenteritis To offer patients single rooms in hospitals is not enough to prevent gastroenteritis. That is shown in a master thesis at Nordic School of Public Health NHV."There must be more preventive measures, where single rooms can be one, to prevent the spreading of infectious diarrhea, says Anita Wang Børseth, Master of Public Health. | 13 Dec 2011 |
| Genetics News | |
| How Do BRCA1 Mutations Harm Breast Cells? Researchers Demonstrate Researchers at the Johns Hopkins Kimmel Cancer Center have demonstrated during their work with breast cells that breast cells become vulnerable to cancer if a single copy of the breast cancer gene BRCA1 is inactivated. | 13 Dec 2011 |
| In Pre-Leukemic Cells, 'PARP' Drug Sabotages DNA Repair Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits of their own DNA, causing these cells to self-destruct. | 13 Dec 2011 |
| In Rat Model Of Lou Gehrig's, Disease Progression Halted Amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease) is an incurable adult neurodegenerative disorder that progresses to paralysis and death. Genetic mutations are the cause of disease in 5% of patients with ALS. | 13 Dec 2011 |
| Gene Inheritance Patterns Influence Age Of Diagnosis In BRCA Families Women who inherit the cancer genes BRCA1 or BRCA2 from their paternal lineage may get a diagnosis a decade earlier than those women who carry the cancer genes from their mother and her ancestors, according to a new study by researchers at the North Shore-LIJ Health System's Monter Cancer Center in Lake Success, NY. | 13 Dec 2011 |
| Researchers Identify Genetic Mutation Responsible For Most Cases Of Waldenstrom's Macroglobulinemia Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom's macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause. | 13 Dec 2011 |
| Clues To Development Of The Pancreas Provided By Rare Genetic Disorder Could Lead To Diabetes Therapy A rare genetic disorder has given researchers at the University of Exeter a surprising insight into how the pancreas develops. The finding provides a clue to how it may be possible to 'programme' stem cells - master cells in the body that can develop into specialised cells - to become pancreatic cells. | 13 Dec 2011 |
| Adults With Hemophilia B Benefit From Gene Therapy Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U. | 13 Dec 2011 |
| Heart Disease News | |
| Physician Bias Leads To Variations In Cardiac Procedures Physician preferences and hospital characteristics influence the type of procedures performed on blockages of the heart, leading to significant variations in rates of bypass, stent or angioplasty procedures, found an article in CMAJ (Canadian Medical Association Journal). | 13 Dec 2011 |
| Risk Of Death And Stroke In Those With Heart Disease Increased By Herbal Amphetamine Chewing the natural stimulant khat increases the risk of death and stroke in patients with heart disease compared to those who are not users, according to new research in Circulation: Journal of the American Heart Association. | 13 Dec 2011 |
| HIV / AIDS News | |
| News From The Journal Of Clinical Investigation : Dec. 12, 2011 IMMUNOLOGY: Finding a new immune function for NEMO Ectodermal dysplasias are a group of inherited conditions in which there is abnormal development and function of the skin, hair, nails, teeth, and/or sweat glands. | 13 Dec 2011 |
| Hypertension News | |
| Blood Pressure Monitoring: Room For Improvement Inaccurate blood pressure measurements due to faulty technique impact hypertension treatment decisionsBecause some clinicians fail to stick to official recommendations for blood pressure monitoring, a number of patients are misclassified, which could have an impact on decisions about their treatment. | 13 Dec 2011 |
| Immune System / Vaccines News | |
| Cancer Vaccine Significantly Reduces Tumor Size An experimental cancer vaccine has been found to reduce tumor size by an average of 80%, researchers from the Mayo Clinic and the University of Georgia reported in Proceedings of the National Academy of Sciences. | 13 Dec 2011 |
| Immune Response To Multiple Myeloma Stimulated By Peptide 'Cocktail' Scientists at Dana-Farber Cancer Institute have created a "cocktail" of immune-stimulating peptides they believe could provoke the body's defenses to attack multiple myeloma in its early "smoldering" phase and slow or prevent the blood cancer. | 13 Dec 2011 |
| News From The Journal Of Clinical Investigation : Dec. 12, 2011 IMMUNOLOGY: Finding a new immune function for NEMO Ectodermal dysplasias are a group of inherited conditions in which there is abnormal development and function of the skin, hair, nails, teeth, and/or sweat glands. | 13 Dec 2011 |
| Can Transplant Recipients Be Weaned Off Their Immunosuppresive Drugs? Transplant surgeons live in the hope that one day they will be able to wean at least some of their patients off the immunosuppressive drugs that must be taken to prevent rejection of a transplanted organ. | 13 Dec 2011 |
| Study Points To Novel Way To Improve Outcomes From Umbilical Cord Blood Transplants A new method to boost the number of immune cells in umbilical cord blood prior to cord blood transplants for cancer patients appears to lead to a quicker rebuilding of a new immune system in the patient's body than with a conventional cord blood transplant procedure, according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting. | 13 Dec 2011 |
| Immune System Repaired In Leukemia Patients Following Chemotherapy A new treatment using leukemia patients' own infection-fighting cells appears to protect them from infections and cancer recurrence following treatment with fludarabine-based chemotherapy, according to new research from the Perelman School of Medicine at the University of Pennsylvania. | 13 Dec 2011 |
| Researchers Say Scar Findings Could Lead To New Therapies Researchers at the Stanford University School of Medicine report that they have identified the molecular pathway through which physical force contributes to scarring in mice."Our study exposes one of the fundamental mechanisms by which the mechanical environment can directly increase inflammation, which is strongly implicated in scarring," said Geoffrey Gurtner, MD, professor and associate chair of surgery. | 13 Dec 2011 |
| Infectious Diseases / Bacteria / Viruses News | |
| Communication Via Tiny Protein Triggers Defensive Response In Plants Scientists have discovered a new signal that helps invading bacteria communicate but also helps targeted rice plants coordinate defensive attacks on the disease-causing invaders, a finding that could lead to new methods of combatting infection not just in plants, but in humans. | 13 Dec 2011 |
| An Easy-To-Use Solution To Make Hospitals Safer According to the World Health Organization, antibiotic-resistant bacteria are one of the top three threats to human health. Patients in hospitals are especially at risk, with almost 100,000 deaths due to infection every year in the U. | 13 Dec 2011 |
| Significant Findings In Foot-And-Mouth Disease Researchers at the University of Leeds have been studying an enzyme - called 3D - which plays a vital role in the replication of the virus behind the disease. They have found that this enzyme forms fibrous structures (or fibrils) during the replication process. | 13 Dec 2011 |
| Liver Disease / Hepatitis News | |
| Can Transplant Recipients Be Weaned Off Their Immunosuppresive Drugs? Transplant surgeons live in the hope that one day they will be able to wean at least some of their patients off the immunosuppressive drugs that must be taken to prevent rejection of a transplanted organ. | 13 Dec 2011 |
| Adults With Hemophilia B Benefit From Gene Therapy Symptoms improved significantly in adults with the bleeding disorder hemophilia B following a single treatment with gene therapy developed by researchers at St. Jude Children's Research Hospital in Memphis and demonstrated to be safe in a clinical trial conducted at the University College London (UCL) in the U. | 13 Dec 2011 |
| Lymphoma / Leukemia / Myeloma News | |
| How Lymphoma Evolves - A Study Of Two Sisters A 41-year-old woman with chronic-phase chronic myeloid leukemia received a bone marrow transplant and subsequent leukocyte infusion from her sister to control her leukemia, however seven years on, both sisters developed follicular lymphoma. | 13 Dec 2011 |
| Immune Response To Multiple Myeloma Stimulated By Peptide 'Cocktail' Scientists at Dana-Farber Cancer Institute have created a "cocktail" of immune-stimulating peptides they believe could provoke the body's defenses to attack multiple myeloma in its early "smoldering" phase and slow or prevent the blood cancer. | 13 Dec 2011 |
| In Pre-Leukemic Cells, 'PARP' Drug Sabotages DNA Repair Looking for ways to halt the uncontrolled growth of cancer cells, scientists at Johns Hopkins have found that a new class of drugs, called PARP inhibitors, may block the ability of pre-leukemic cells to repair broken bits of their own DNA, causing these cells to self-destruct. | 13 Dec 2011 |
| A Two-Faced Leukemia? One kind of leukemia sometimes masquerades as another, according to a study published online this week in the Journal of Experimental Medicine*.Leukemia results when normal immune cells accumulate mutations that drive uncontrolled growth. | 13 Dec 2011 |
| Researchers Identify Genetic Mutation Responsible For Most Cases Of Waldenstrom's Macroglobulinemia Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenstrom's macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause. | 13 Dec 2011 |
| AML Patients Have High Response Rate With Vorinostat Added To Treatment Adding a drug that activates genes to frontline combination therapy for acute myeloid leukemia resulted in an 85 percent remission rate after initial treatment, researchers at The University of Texas MD Anderson Cancer Center reported at the 53rd Annual Meeting of the American Society of Hematology. | 13 Dec 2011 |
| "Twinning" U.S.-Based And Rwandan Physicians Improves Lymphoma Outcomes In Children In an African county lacking any specialists in children's cancers, a team approach that "twins" Rwandan physicians with Boston-based pediatric oncologists has shown it can deliver expert, curative care to young patients stricken with lymphoma. | 13 Dec 2011 |
| Immune System Repaired In Leukemia Patients Following Chemotherapy A new treatment using leukemia patients' own infection-fighting cells appears to protect them from infections and cancer recurrence following treatment with fludarabine-based chemotherapy, according to new research from the Perelman School of Medicine at the University of Pennsylvania. | 13 Dec 2011 |
| B Cell Receptor Inhibitor Causes Chronic Lymphocytic Leukemia Remission PCI-32765 applies molecularly aimed attack to disease usually treated with chemotherapy combinations A new, targeted approach to treating chronic lymphocytic leukemia has produced durable remissions in a Phase I/II clinical trial for patients with relapsed or resistant disease, investigators report at the 53rd Annual Meeting of the American Society of Hematology. | 13 Dec 2011 |
| How Patients Will Respond To Immunomodulator Therapy For Multiple Myeloma Research on the same protein that was a primary mediator of the birth defects caused by thalidomide now holds hope in the battle against multiple myeloma, says the study's senior investigator, Keith Stewart, M. | 13 Dec 2011 |
| Novel Experimental Agent Is Highly Active In Chronic Lymphocytic Leukemia Patients, Interim Study Shows An interim analysis of a phase Ib/II clinical trial indicates that a novel experimental agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other therapy. | 13 Dec 2011 |
| Medical Devices / Diagnostics News | |
| Stop Misbranding Lap-Band In Your Advertising, FDA Warns Companies 1-800-GET-THIN LLC has been warned, along with eight surgical centers in California, to stop misleading people in their advertising about the Lap-Band, a medical device approved by the FDA to help obese adults lose weight. | 13 Dec 2011 |
| Electrical Activity In The Brain Likened To An Orchestra Researchers at the Norwegian University of Life Sciences (UMB) have developed a new method for detailed analyses of electrical activity in the brain. The method, recently published in Neuron, can help doctors and researcher to better interpret brain cell signals. | 13 Dec 2011 |
| MRI / PET / Ultrasound News | |
| Lower Back Pain - MRI Does Not Improve Outcomes For Epidural Steroid Injection Candidates According to an investigation published Online First by the Archives of Internal Medicine, one of the JAMA/Archives journals, magnetic resonance imaging (MRI) prior to administration of epidural steroid injections (ESI), does not seem to improve outcomes for individuals with chronic lower back pain or for those with conditions like sciatica, and only has a small effect on the physician's decision making. | 13 Dec 2011 |
| Costly Diagnostic MRI Tests Unnecessary For Many Back Pain Patients Johns Hopkins-led research suggests that routine MRI imaging does nothing to improve the treatment of patients who need injections of steroids into their spinal columns to relieve pain. Moreover, MRI plays only a small role in a doctor's decision to give these epidural steroid injections (ESIs), the most common procedure performed at pain clinics in the United States. | 13 Dec 2011 |
| Increasing Number Of Imaging Visits Faced By Breast Cancer Patients Before Surgery Breast cancer patients frequently undergo imaging like mammograms or ultrasounds between their first breast cancer-related doctor visit and surgery to remove the tumor. Evaluations of these scans help physicians understand a person's disease and determine the best course of action. | 13 Dec 2011 |
| MRSA / Drug Resistance News | |
| An Easy-To-Use Solution To Make Hospitals Safer According to the World Health Organization, antibiotic-resistant bacteria are one of the top three threats to human health. Patients in hospitals are especially at risk, with almost 100,000 deaths due to infection every year in the U. | 13 Dec 2011 |
| Neurology / Neuroscience News | |
| Parkinsons' - Brain Volume Decrease And Cognitive Decline Linked According to a study published in the December issue of Archives of Neurology, one of the JAMA/Archives journals, individuals who suffer with Parkinson disease-related dementia seem to have increased brain atrophy in the parietal, hippocampal, temporal lobes, as well as decreased prefrontal cortex volume than individuals with Parkinson disease without dementia. | 13 Dec 2011 |
| Simple, Model-Free Analysis Of Voltage-Gated Channels A new study in the Journal of General Physiology* provides fresh insight into voltage-gated channels - transmembrane ion channels that play a critical role in the function of neuronal and muscle tissue. | 13 Dec 2011 |
| Understanding How Brain Tumors Invade Scientists have pinpointed a protein that allows brain tumors to invade healthy brain tissue, according to work published this week in the Journal of Experimental Medicine*.40% of a common but deadly type of brain tumor - called glioblastoma multiforme (GBM) - have mutations in a gene that encodes a protein called epidermal growth factor receptor (EGFR). | 13 Dec 2011 |
| Cognitive Problems Still Evident Several Years After Breast Cancer Treatment A new analysis has found that breast cancer survivors may experience problems with certain mental abilities several years after treatment, regardless of whether they were treated with chemotherapy plus radiation or radiation only. | 13 Dec 2011 |
| Electrical Activity In The Brain Likened To An Orchestra Researchers at the Norwegian University of Life Sciences (UMB) have developed a new method for detailed analyses of electrical activity in the brain. The method, recently published in Neuron, can help doctors and researcher to better interpret brain cell signals. | 13 Dec 2011 |
| In Rat Model Of Lou Gehrig's, Disease Progression Halted Amyotrophic lateral sclerosis (ALS; also known as Lou Gehrig's disease) is an incurable adult neurodegenerative disorder that progresses to paralysis and death. Genetic mutations are the cause of disease in 5% of patients with ALS. | 13 Dec 2011 |
| Brain Tumor Chemotherapy Resistance Prediction Glioblastoma multiforme (GBM) is the most common and lethal of all human brain tumors that originate in the brain. For most patients, treatment involves surgery followed by both radiation therapy and chemotherapy with temozolomide. | 13 Dec 2011 |
| Structural Pattern Uncovers Brain Atrophy In Parkinson's Atrophy in the hippocampus, the region of the brain known for memory formation and storage, is evident in Parkinson's disease (PD) patients with cognitive impairment, including early decline known as mild cognitive impairment (MCI), according to a study by researchers in the Perelman School of Medicine at the University of Pennsylvania. | 13 Dec 2011 |
| RUB Researchers Decipher The Role Of Proteins In The Cell Environment How astrocytes, certain cells of the nervous system, are generated was largely unknown up to now. Bochum's researchers have now investigated what influence the cell environment, known as the extracellular matrix, has on this process. | 13 Dec 2011 |
| If You Care, Yawn Back! Everybody knows that yawning is contagious. When a person yawns, other people can respond by yawning. What wasn't known is that "yawn transmission" is more frequent, and faster, between people sharing an empathic bond: close friends, kin, and mates. | 13 Dec 2011 |
| Erythropoietin May Pose A Risk To Blood Vessels In The Brain And Body Erythropoietin or EPO might be considered a "performance enhancing" substance for athletes, but new research published online in /i>The FASEB Journal shows that these enhancements come at a high cost - increased risk of vascular problems in the brain. | 13 Dec 2011 |
| Swarms Of Bees Could Unlock Secrets To Human Brains Scientists at the University of Sheffield believe decision making mechanisms in the human brain could mirror how swarms of bees choose new nest sites.Striking similarities have been found in decision making systems between humans and insects in the past but now researchers believe that bees could teach us about how our brains work. | 13 Dec 2011 |
| Preventing A Traumatism From Establishing Itself And Becoming Pathological The study, initiated by the Swiss researchers and published in Nature, constitutes ground-breaking work in exploring emotions in the brain.Anxiety disorders constitute a complex family of pathologies affecting about 10% of adults. | 13 Dec 2011 |
| Nursing / Midwifery News | |
| Cellular Processing Of Proteins Found In Congolese Child Birthing Tea Many plants produce compounds that serve as a defense against predators or pathogens. Some are also used by humans for a variety of beneficial purposes, such as in medicines. As recently as the early 1990s, a unique class of proteins previously unknown to science, the cyclotides, was discovered. | 13 Dec 2011 |
| Obesity / Weight Loss / Fitness News | |
| Stop Misbranding Lap-Band In Your Advertising, FDA Warns Companies 1-800-GET-THIN LLC has been warned, along with eight surgical centers in California, to stop misleading people in their advertising about the Lap-Band, a medical device approved by the FDA to help obese adults lose weight. | 13 Dec 2011 |
| Model Developed For Future Obesity Drug Testing Scientists have shown that over expression of a specific human protein in the brain of a transgenic mouse leads to overeating and excessive body weight gain.Led by researchers at the University of Maryland School of Pharmacy, the mouse study may be ideal, they say, for testing new obesity controlling drugs and studies of the condition itself. | 13 Dec 2011 |
| Ovarian Cancer News | |
| Vaccine Developed That Attacks Breast Cancer In Mice; Implications For Ovarian, Colorectal And Pancreatic Cancers Researchers from the University of Georgia and the Mayo Clinic in Arizona have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases - including those that are resistant to common treatments. | 13 Dec 2011 |
| Gene Inheritance Patterns Influence Age Of Diagnosis In BRCA Families Women who inherit the cancer genes BRCA1 or BRCA2 from their paternal lineage may get a diagnosis a decade earlier than those women who carry the cancer genes from their mother and her ancestors, according to a new study by researchers at the North Shore-LIJ Health System's Monter Cancer Center in Lake Success, NY. | 13 Dec 2011 |
| Pain / Anesthetics News | |
| Prevalence Of Chronic Pain In Children And Teenagers Growing Persistent or recurring chronic pain in children may result in missing school and withdrawing from social activities. They are also at risk of developing personalized symptoms like anxiety. A group of researchers has established that more children currently suffer from chronic pain and that chronic pain is more prevalent in girls than boys. | 13 Dec 2011 |
| Lower Back Pain - MRI Does Not Improve Outcomes For Epidural Steroid Injection Candidates According to an investigation published Online First by the Archives of Internal Medicine, one of the JAMA/Archives journals, magnetic resonance imaging (MRI) prior to administration of epidural steroid injections (ESI), does not seem to improve outcomes for individuals with chronic lower back pain or for those with conditions like sciatica, and only has a small effect on the physician's decision making. | 13 Dec 2011 |
| Pancreatic Cancer News | |
| Vaccine Developed That Attacks Breast Cancer In Mice; Implications For Ovarian, Colorectal And Pancreatic Cancers Researchers from the University of Georgia and the Mayo Clinic in Arizona have developed a vaccine that dramatically reduces tumors in a mouse model that mimics 90 percent of human breast and pancreatic cancer cases - including those that are resistant to common treatments. | 13 Dec 2011 |
| Parkinson's Disease News | |
| Parkinsons' - Brain Volume Decrease And Cognitive Decline Linked According to a study published in the December issue of Archives of Neurology, one of the JAMA/Archives journals, individuals who suffer with Parkinson disease-related dementia seem to have increased brain atrophy in the parietal, hippocampal, temporal lobes, as well as decreased prefrontal cortex volume than individuals with Parkinson disease without dementia. | 13 Dec 2011 |
| Structural Pattern Uncovers Brain Atrophy In Parkinson's Atrophy in the hippocampus, the region of the brain known for memory formation and storage, is evident in Parkinson's disease (PD) patients with cognitive impairment, including early decline known as mild cognitive impairment (MCI), according to a study by researchers in the Perelman School of Medicine at the University of Pennsylvania. | 13 Dec 2011 |
| Pediatrics / Children's Health News | |
| Working Moms Are Happier And Healthier A report published by The American Psychological Association shows that mothers who maintain their jobs while their children are in infancy and pre-school years are happier and healthier than their more traditional stay at home peers. | 13 Dec 2011 |
| Prevalence Of Chronic Pain In Children And Teenagers Growing Persistent or recurring chronic pain in children may result in missing school and withdrawing from social activities. They are also at risk of developing personalized symptoms like anxiety. A group of researchers has established that more children currently suffer from chronic pain and that chronic pain is more prevalent in girls than boys. | 13 Dec 2011 |
| Childhood Cancer Survivors' Exposure To Chemotherapy, Radiation Does Not Increase Risk Of Birth Defects In Their Children A large, retrospective study shows that children of childhood cancer survivors who received prior treatment involving radiation to testes or ovaries and/or chemotherapy with alkylating agents do not have an increased risk for birth defects compared to children of survivors who did not have such cancer treatment. | 13 Dec 2011 |
| Surprisingly Early Gift Of Gab Revealed By Baby Lab From the moment they're born, babies are highly attuned to communicate and motivated to interact. And they're great listeners.New research from the University of Notre Dame shows that during the first year of life, when babies spend so much time listening to language, they're actually tracking word patterns that will support their process of word- learning that occurs between the ages of about 18 months and two years. | 13 Dec 2011 |
| Pharma Industry / Biotech Industry News | |
| Linagliptin Combined With Metroformin Demonstrates Meaningful Glycemic Control Improvement Boehringer Ingelheim and Eli Lilly and Company announced their results of a 24-week open label arm of a phase III study for linagliptin in initial combination with metformin at the International Diabetes Federation (IDF) World Diabetes Congress in Dubai. | 13 Dec 2011 |
| Little-Studied Cellular Mechanism Elevated To Potential Drug Target For years, science has generally considered the phosphorylation of proteins -- the insertion of a phosphorous group into a protein that turns it on or off -- as perhaps the factor regulating a range of cellular processes from cell metabolism to programmed cell death. | 13 Dec 2011 |
| Pharmacy / Pharmacist News | |
| When Planning For Terrorist Chemical Weapons, Pharmacists May Be Crucial Terrorist attacks with chemical weapons are a real possibility, according to a study that appears in the online open access Journal of Pharmacy Practice, published by SAGE. Thanks to their extensive knowledge of toxic agents, and how to treat those who have been exposed, pharmacists are an invaluable resource in the event of an actual or potential chemical weapons attack. | 13 Dec 2011 |
| Psychology / Psychiatry News | |
| Working Moms Are Happier And Healthier A report published by The American Psychological Association shows that mothers who maintain their jobs while their children are in infancy and pre-school years are happier and healthier than their more traditional stay at home peers. | 13 Dec 2011 |
| FDA Committee Recommends Approval Of ADASUVE For Bipolar And Schizophrenia The Psychopharmacologic Drugs Advisory Committee (PDAC) of the U.S. Food and Drug Administration (FDA) voted to recommend that ADASUVE(TM) (Staccato® loxapine) be approved for use as a single dose in 24 hours. | 13 Dec 2011 |
| ADHD Drugs Do Not Raise Stroke, Heart Attack Or Sudden Cardiac Death Risk Young and middle-aged adults who are prescribed ADHD (attention deficit/hyperactivity disorder) drugs do not have a higher chance of developing serious cardiovascular events, such as sudden cardiac death, heart attack or stroke, researchers from Kaiser Permanente Northern California, Oakland, reported in JAMA (Journal of the American Medical Association). | 13 Dec 2011 |
| Public Health News | |
| Communication Via Tiny Protein Triggers Defensive Response In Plants Scientists have discovered a new signal that helps invading bacteria communicate but also helps targeted rice plants coordinate defensive attacks on the disease-causing invaders, a finding that could lead to new methods of combatting infection not just in plants, but in humans. | 13 Dec 2011 |
| Radiology / Nuclear Medicine News | |
| Brain Tumor Chemotherapy Resistance Prediction Glioblastoma multiforme (GBM) is the most common and lethal of all human brain tumors that originate in the brain. For most patients, treatment involves surgery followed by both radiation therapy and chemotherapy with temozolomide. | 13 Dec 2011 |
| Increasing Number Of Imaging Visits Faced By Breast Cancer Patients Before Surgery Breast cancer patients frequently undergo imaging like mammograms or ultrasounds between their first breast cancer-related doctor visit and surgery to remove the tumor. Evaluations of these scans help physicians understand a person's disease and determine the best course of action. | 13 Dec 2011 |
| Respiratory / Asthma News | |
| Trial With Salbutamol For Acute Respiratory Distress Syndrome Stopped - Mortality Rose, Outcomes No Better A trial evaluating the intravenous infusion of salbutamol in patients with acute respiratory distress syndrome (ARDS) was stopped after patients receiving the drug had increased mortality and showed no improvement in outcomes. | 13 Dec 2011 |
| Seniors / Aging News | |
| Cancer Screening In Older Patients Very Common U.S. Preventive Services Task Force guidelines recommend against routine cancer screening, especially for breast, cervical, colorectal and prostate cancer, but adults 75 and older are still receiving regular cancer screenings. | 13 Dec 2011 |
| Sports Medicine / Fitness News | |
| Erythropoietin May Pose A Risk To Blood Vessels In The Brain And Body Erythropoietin or EPO might be considered a "performance enhancing" substance for athletes, but new research published online in /i>The FASEB Journal shows that these enhancements come at a high cost - increased risk of vascular problems in the brain. | 13 Dec 2011 |
| Stem Cell Research News | |
| Therapy Improves Stem Cell Engraftment In Umbilical Cord Blood Transplant Recipients A therapy involving a natural compound may improve the ability of stem cells from umbilical cord blood to engraft in patients receiving a stem cell transplant for cancer or other diseases, a phase I clinical trial led by Dana-Farber Cancer Institute scientists indicates. | 13 Dec 2011 |
| Stroke News | |
| Risk Of Death And Stroke In Those With Heart Disease Increased By Herbal Amphetamine Chewing the natural stimulant khat increases the risk of death and stroke in patients with heart disease compared to those who are not users, according to new research in Circulation: Journal of the American Heart Association. | 13 Dec 2011 |
| Transplants / Organ Donations News | |
| Can Transplant Recipients Be Weaned Off Their Immunosuppresive Drugs? Transplant surgeons live in the hope that one day they will be able to wean at least some of their patients off the immunosuppressive drugs that must be taken to prevent rejection of a transplanted organ. | 13 Dec 2011 |
| Therapy Improves Stem Cell Engraftment In Umbilical Cord Blood Transplant Recipients A therapy involving a natural compound may improve the ability of stem cells from umbilical cord blood to engraft in patients receiving a stem cell transplant for cancer or other diseases, a phase I clinical trial led by Dana-Farber Cancer Institute scientists indicates. | 13 Dec 2011 |
| Tropical Diseases News | |
| Malaria Global Mortality Down 25% In Ten Years Mortality rates for malaria have dropped by over 25% worldwide since the beginning of the millennium, according to World Malaria Report 2011, issued by WHO (World Health Organization). Progress in Africa has been especially impressive, where death rates have dropped by 33% since 2000. | 13 Dec 2011 |
| Vascular News | |
| Outpatients Experience The Most Cancer-Related Blood Clots In a study of nearly 18,000 cancer patients, University of Rochester Medical Center researchers found that when blood clots develop - a well-known and serious complication of cancer treatment - 78 percent of the time they occur when a person is out of the hospital, at home or elsewhere, while on chemotherapy. | 13 Dec 2011 |
| Erythropoietin May Pose A Risk To Blood Vessels In The Brain And Body Erythropoietin or EPO might be considered a "performance enhancing" substance for athletes, but new research published online in /i>The FASEB Journal shows that these enhancements come at a high cost - increased risk of vascular problems in the brain. | 13 Dec 2011 |
| Veterinary News | |
| Significant Findings In Foot-And-Mouth Disease Researchers at the University of Leeds have been studying an enzyme - called 3D - which plays a vital role in the replication of the virus behind the disease. They have found that this enzyme forms fibrous structures (or fibrils) during the replication process. | 13 Dec 2011 |
| Water - Air Quality / Agriculture News | |
| Communication Via Tiny Protein Triggers Defensive Response In Plants Scientists have discovered a new signal that helps invading bacteria communicate but also helps targeted rice plants coordinate defensive attacks on the disease-causing invaders, a finding that could lead to new methods of combatting infection not just in plants, but in humans. | 13 Dec 2011 |
| Women's Health / Gynecology News | |
| Cellular Processing Of Proteins Found In Congolese Child Birthing Tea Many plants produce compounds that serve as a defense against predators or pathogens. Some are also used by humans for a variety of beneficial purposes, such as in medicines. As recently as the early 1990s, a unique class of proteins previously unknown to science, the cyclotides, was discovered. | 13 Dec 2011 |
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